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Primary Features of RLS
• An urge to move, usually due to uncomfortable sensations that occur primarily in the legs
• Motor restlessness, expressed as activity, that relieves the urge to move
• Worsening of symptoms by relaxation
• Variability over the course of the day-night cycle, with symptoms worse in the evening and early in the night
Associated Features of RLS
• Periodic limb movements in sleep
• Sleep disturbance especially difficulty in sleep initiation
• Dyskinesias while awake that occur almost exclusively at rest
• Positive family history
• Exclusion of potential underlying causes of RLS
• Onset at any age with typically chronic and progressive course and occasional remissions
Information for Patients and Family Members
Living with Restless Legs Syndrome – This brochure provides a good introduction to RLS and is written for patients. It is available in English, French, German, Icelandic, Italian, and Spanish. You may download a PDF (see the list below).
Information for Healthcare Providers
RLS Medical Bulletin – Approved and reviewed by the RLS Foundation’s Medical Advisory Board, this comprehensive resource discusses prevalence, pathophysiology, genetics, diagnosis, treatment, and special concerns for patients with RLS.
For More Information
Please contact the RLS Foundation for more information on their publications and resources for patients and healthcare providers.
This website is designed to provide information about the current understanding of RLS. Laypeople who read this information are warned against making any changes in their treatment based on this information without consulting their healthcare provider. While the IRLSSG and the RLS Foundation have made every effort to ensure the accuracy of this information, medical knowledge changes quickly and therefore practitioners are urged to continually seek up-to-date information. Some treatments discussed in these materials, while in line with accepted medical practice, may not be approved by the U.S. Food and Drug Administration for the described uses. The RLS Foundation and the IRLSSG, their officers, directors, employees or agents, do not warrant or guarantee the accuracy or completeness of its information or services and specifically disclaims any liability therefore. Back to top.